Endocrine Abstracts

Aim: The aim of the study was to evaluate the birth weight of children born to women with AITD compared to with those born to women without AITD.Material and methods: The study included 596 pregnant women and their children in 2007–2015. The patients were divided into two groups. The first (group A) consisted of 191 pregnant women with chronic autoimmune thyroiditis and their children, while the second (group B) consisted of 405 pregnant women witho...

Isolated hypogonadotropic hypogonadism (IHH) is caused by impaired gonadoliberin (GnRH) gene regulation, synthesis or secretion of GnRH. Genetic factors of more than 50% of the IHH are still unknown. One the most common types of IHH is the Kallmann syndrome (KS) associated with anosmia or hyposmia. In view of technological progress and new possibilities for detecting changes in human genome a comprehensive targeted analysis using next-generation sequencing (NGS) was carried ou...

Iodine deficiency is considered the most common preventable cause of brain damage worldwide. It is particularly important during pregnancy, as it influences not only mothers but their fetuses as well. The Polish model of iodine prophylaxis is based on obligatory household salt iodization and recommendation of iodine-containing supplements for pregnant women. The aim of the study was to assess the current iodine status of pregnant women and to compare it with earlier results.</...